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2025 College Football Playoff Quarterfinal Odds: A Professional Breakdown

The 2025 College Football Playoff has advanced to the quarterfinal stage, setting the scene for four pivotal matchups. This analysis provides a professional overview of the betting odds, point spreads, and over/under totals for each game, as reported by DraftKings Sportsbook. We examine the key lines for the Cotton, Orange, Rose, and Sugar Bowls, offering context on the teams and the implications of the odds for fans and observers of the sport.

The College Football Playoff has reached its critical quarterfinal round, where national championship aspirations are put to the ultimate test. As the field narrows, the betting markets provide a quantitative lens through which to view each matchup, reflecting perceived strengths, weaknesses, and potential game dynamics. This professional overview breaks down the latest odds and lines for the 2025 CFP quarterfinals, offering clarity on the spreads, moneylines, and totals that define the betting landscape for these high-stakes games.

College Football Playoff trophy on field
The College Football Playoff National Championship trophy.

Quarterfinal Game Odds and Analysis

As of January 1, 2026, the odds from DraftKings Sportsbook paint a picture of four distinct contests. The lines account for first-round performances, historical matchups, and team momentum heading into this decisive stage of the tournament.

Cotton Bowl: No. 10 Miami vs. No. 2 Ohio State

The opening quarterfinal on December 31st saw a stunning result, with No. 10 Miami defeating No. 2 Ohio State by a score of 24-14. According to the pre-game odds, Ohio State was favored by 9.5 points, a spread that Miami easily covered with their 10-point victory. The game's total points line was set at 40.5, and the combined 38 points meant the 'under' hit in this contest.

Ohio State Buckeyes football helmet
Ohio State Buckeyes football helmet.

Orange Bowl: No. 5 Oregon vs. No. 4 Texas Tech

In the first January 1st game, the No. 5 Oregon Ducks delivered a commanding 23-0 shutout victory over the No. 4 Texas Tech Red Raiders. Oregon entered the game as a 2.5-point favorite and covered that spread convincingly. The over/under for the game was set at a relatively high 50.5 points, but the defensive struggle resulted in a clear 'under' outcome.

Rose Bowl: No. 9 Alabama vs. No. 1 Indiana

The Rose Bowl featured a dominant performance from the top-ranked Indiana Hoosiers, who overwhelmed the No. 9 Alabama Crimson Tide 38-3. Indiana was favored by 7.5 points and covered that spread with ease. The total points line was 46.5, and with only 41 total points scored, this game also resulted in an 'under' hitting the board.

Indiana Hoosiers football helmet
Indiana Hoosiers football helmet.

Sugar Bowl: No. 6 Ole Miss vs. No. 3 Georgia

The final quarterfinal pits the No. 6 Ole Miss Rebels against the No. 3 Georgia Bulldogs in the Sugar Bowl. Georgia is currently installed as a 6-point favorite. The moneyline odds stand at Georgia -230 and Ole Miss +190, indicating the Bulldogs are strong favorites to advance. The over/under total is set at 54.5 points. This matchup is a rematch of a regular-season thriller on October 18, where Georgia narrowly defeated Ole Miss 43-35 after trailing in the third quarter. Ole Miss enters with momentum after a decisive 41-10 first-round win over Tulane.

Context and Implications of the Odds

Betting odds serve as more than just a guide for wagers; they are a reflection of collective expert opinion on team matchups, strengths, and potential game flow. The spreads for these quarterfinals highlighted expectations of defensive battles, as evidenced by three of the four games resulting in 'under' outcomes relative to their totals. The rematch between Georgia and Ole Miss in the Sugar Bowl presents the most intriguing line, with the relatively tight 6-point spread acknowledging Ole Miss's competitive performance earlier in the season and their potent offense.

Conclusion

The 2025 College Football Playoff quarterfinals have provided dramatic results that both confirmed and defied the pre-game betting odds. While favorites like Oregon and Indiana covered their spreads, the major upset by Miami over Ohio State serves as a reminder of the unpredictable nature of postseason football. As the tournament progresses, the odds will continue to evolve, offering a constantly shifting benchmark against which to measure team performance and championship potential. All odds information is sourced from DraftKings Sportsbook via FOX Sports.

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