Lions vs Packers Week 13 Preview: Betting Odds, Predictions and Key Matchups

The Detroit Lions and Green Bay Packers prepare for a pivotal NFC North showdown on Thanksgiving Day 2025, with both teams entering Ford Field with identical 7-4 records. This divisional rivalry takes center stage during the holiday weekend, featuring two teams battling for playoff positioning in the competitive NFC. The Lions enter as slim 2.5-point favorites in what promises to be one of the week's most compelling matchups.

Game Details and Betting Lines

The Week 13 matchup kicks off at 1 p.m. ET on Thursday, November 27, 2025, from Ford Field in Detroit, Michigan. According to FOX Sports betting analysis, the Lions are favored by 2.5 points with the total points over/under set at 49.5. Detroit has shown strong performance as favorites this season, covering the spread in five of seven games when favored by 2.5 points or more. The Packers, meanwhile, have compiled a 4-7 record against the spread this year.

Team Statistical Comparison

Detroit Lions Offensive Strengths

The Lions boast the NFL's second-ranked scoring offense, averaging 29.6 points per game through 11 contests. Their balanced attack features the league's third-best rushing offense (139.8 yards per game) complemented by the eighth-ranked passing attack (238.6 yards per game). Quarterback Jared Goff has been particularly effective, ranking seventh in passing yards (2,769) and second in touchdown passes (23) with only five interceptions.

Green Bay Packers Defensive Prowess

The Packers counter with one of the league's top defensive units, ranking fifth in both points allowed (18.4 per game) and passing defense (182.3 yards per game). Their run defense has been equally impressive, surrendering just 96.5 rushing yards per game (sixth in NFL). This sets up an intriguing matchup between Detroit's high-powered offense and Green Bay's stingy defense.

Key Players to Watch

Detroit's offensive success hinges on running back Jahmyr Gibbs, who ranks third in the NFL with 951 rushing yards and leads the league with 6.1 yards per attempt. His dual-threat capability includes 48 receptions for 379 yards and three touchdowns. Wide receiver Amon-Ra St. Brown provides another weapon, ranking fourth in receiving yards (884) with nine touchdown catches.

Green Bay's offense relies on quarterback Jordan Love, who has thrown for 2,560 yards with 15 touchdowns and only three interceptions. Running back Josh Jacobs has been particularly effective in the red zone, scoring 11 rushing touchdowns while accumulating 648 rushing yards. The Packers' balanced attack will test Detroit's middle-of-the-pack defense.

Prediction and Analysis

Based on recent trends and statistical analysis, the Lions appear positioned to cover the 2.5-point spread at home. Detroit has won three of the last five meetings between these division rivals, outscoring Green Bay 127-121 in those contests. The Lions' offensive firepower, combined with their success as favorites this season, gives them the edge in this crucial divisional matchup. The prediction favors Detroit 26-21, with the game staying under the 49.5-point total as both defenses make key stops in critical situations.

This Thanksgiving Day matchup carries significant implications for the NFC North standings and playoff positioning. With both teams demonstrating strengths on opposite sides of the ball, the game likely comes down to which unit can impose its will more effectively. The Lions' home-field advantage and proven ability to perform as favorites provide the slight edge in what promises to be a hard-fought divisional battle.