Read on nature.comNature Publishes Author Correction for Groundbreaking Antimalarial Research
Nature has published an author correction for the 2016 study 'Diversity-oriented synthesis yields novel multistage antimalarial inhibitors.' The correction addresses a duplicated image in Extended Data Fig. 3c, where the 'Chloroquine' image was mistakenly replaced with a duplicate of the 'BRD7929, 25' image. This correction notice ensures scientific accuracy while maintaining the integrity of the original research findings. The study involved researchers from multiple prestigious institutions including Harvard, MIT, and Duke University, focusing on developing new antimalarial compounds through innovative synthesis approaches.
In a recent development for the scientific community, Nature has published an author correction for the groundbreaking 2016 research paper titled 'Diversity-oriented synthesis yields novel multistage antimalarial inhibitors.' This correction, published on November 28, 2025, addresses a specific error in the original publication while maintaining the scientific validity of the research findings.
Understanding the Correction
The correction specifically addresses an issue in Extended Data Fig. 3c of the original publication. According to the official correction notice, the 'Day 11' row contained a duplicated image where the 'Chloroquine' image was mistakenly replaced with a duplicate of the 'BRD7929, 25' image from the same row. The correct 'Chloroquine' image has now been properly documented in the correction notice.
Research Significance
The original study represented a significant advancement in antimalarial drug discovery. The research focused on diversity-oriented synthesis approaches to develop novel inhibitors that target multiple stages of the malaria parasite's life cycle. This methodology represented an innovative approach to combating drug-resistant strains of malaria, which remains a major global health challenge.
Collaborative Research Effort
The study involved an extensive collaboration between multiple prestigious institutions, including the Broad Institute of Harvard and MIT, Harvard T.H. Chan School of Public Health, Duke University, University of California San Diego, and international partners from India, Australia, and the Netherlands. This global collaboration highlights the importance of international cooperation in addressing pressing global health issues like malaria.
Scientific Integrity and Transparency
The publication of this correction demonstrates the scientific community's commitment to transparency and accuracy in research reporting. While the original figure cannot be directly replaced due to the age of the article, the correction notice serves to properly document and amend the error, ensuring that future researchers have access to accurate information.
This approach maintains the integrity of the scientific record while acknowledging that even high-impact research may contain minor errors that require correction. The prompt acknowledgment and documentation of such errors strengthen the reliability of scientific literature and contribute to the overall advancement of knowledge in the field.
